Microbiology, Infectious Diseases and Immunology


We, the scientists at the Institute of Microbiology, Infectious Diseases and Immunology aim to perform groundbreaking research into the interactions between microorganisms and the innate immune system, in particular at border surfaces with the environment. We are eager to open new frontiers for research and approach unresolved issues in microbiology, infectious diseases, immunology and epithelial cell biology. Barrier surfaces such as those of the skin, intestine and lungs are continuously exposed to the environment. For example, they are densely colonized by complex consortia of bacteria, fungi, viruses and parasites and are in contact with a multitude of environmental factors (e.g., diets, light, UV irradiation).

We hypothesize that over millions of years of co-evolution of multicellular organisms with their environments, signaling networks involving components of the innate immune system have been selected that are believed to shield the host against continuous threats to its integrity and, thereby, improve its fitness, a process often referred to as adaptation.

We postulate that the recent dramatic increase of immune-mediated diseases (e.g., inflammatory bowel diseases, allergies, multiple sclerosis, metabolic diseases) reflects unsuccessful adaptation of the immune system to the environment. The mission of the Institute is to establish a multidisciplinary center of excellence for research on host-microbe and host-environment interactions. The new insights gained should fundamentally change our scientific thinking and may substantially contribute to future medical practice to prevent infectious and immune-mediated diseases.

Find here the latest Publications

Cosovanu C and Neumann C. 
Front.Immunol. 20 October 2020
The Many Functions of Foxp3+ Regulatory T Cells in the Intestine
Barrientos G, …, Conrad ML
Sci Rep. 2020; 10: 15243. Published online 2020 Sep 17
Changes in subclass-specific IgG Fc glycosylation associated with the postnatal maturation of the murine immune system
Schaupp L et al.
Cell. Article in press, available online 6 May 2020
Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells

 BIH paper of the month                       May 2020  
Diefenbach A, Gnafakis S, Shomrat O.
Immunity. 2020 Mar 17
Innate Lymphoid Cell-Epithelial Cell Modules Sustain Intestinal Homeostasis
Alhasan M, Conrad ML, Heimesaat M,
Bereswill S et al.
Allergy. Epub Feb 2020, print August 2020
Antibiotic use during pregnancy increases offspring asthma severity in a dose-dependent manner.

What we do

» Development and Function of the Innate Immune Sytem                                                        » Mucosal Immunology
» Crosstalk between the Nervous and the Immune System                  » Role of the Microbota in Health and Disease
» Gastrointestinal Microbiology                                                                                          » Reproductive Immunology
» Biofilm Formation                                                                                                                      » Molecular Mycology
» Infection Epidemiology                                                                                                                    » Host Septomics

Learn More
3 ERC Grantees
1 Emmy-Noether-Program Recipient

DFG Priority Program
“SPP 1937 on Innate Lymphoid Cells”

Web of Science
Highly Cited Researcher


and Projects

Conrad Lab

Reproductive Immunology

Diefenbach Lab

Development and function of the innate immune system

Dürr Lab

Mucosal Immunity

Gräser Lab

Molecular Mycology

Heimesaat and Bereswill Lab

Gastrointestinal Microbiology

Hamann Lab

Genetic variance within the innate immune system

Jordan Lab

Laboratory of Microbiology, Metabolism & Inflammation (LoMMI)

Klose Lab

Neuro-immune Interactions

Moter Lab


Neumann Lab

Lymphocyte Biology and Microenvironment

Stamatiades Lab

Tissue Monitoring by Macrophages

Triantafyllopoulou Lab

Innate Immunity in Rheumatic Diseases

Feldmeier Lab (affiliated)

Neglected Tropical Diseases

Schumann Lab (affiliated)

Host-Pathogen Interaction

Slevogt Lab (affiliated)

Host Septomics



Berlin, 07.05.2020 The microbiome regulates the fitness of the immune system Working alongside colleagues in Mainz, Bern, Hannover and Bonn, researchers from Charité – Universitätsmedizin Berlin, the Berlin Institute of[…]

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Joint CBF seminar series

Please find here the latest information on our internal and external speakers within the framework of our Joint CBF seminar series with a focus on immunology, usually taking place on[…]

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Our Team

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Contact us

We are always interested in applications from master and PhD students

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