“Host Septomics – research group for infection and microbiom research” analyses the mechanism of the innate immune response of the host to microbial associated infections on cellular and molecular level. A special focus is placed on the acute and chronical infections of airways and the lung. Different aspects of the complex interaction between pathogens, microbiome and various immune cells are characterised and analysed with cutting-edge methods of next generation sequencing, mass spectrometry as well as molecular biology. We aim to identify new clinical parameters for the diagnosis and the follow-up of pulmonary inflammation as well as the development of new therapeutic strategies.